Lysine is not a cure for cold sores, but it may help prevent and shorten the duration of an outbreak. A person should continue to take any antiviral medications a doctor prescribes for their cold sores. Those interested in adding lysine supplements to their routine should speak to their doctor beforehand.
How long does lysine take to work on a cold sore? Older research shows supplementing with lysine shortens the duration of a cold sore. Cold sores can last up to 21 days. However, two studies noticed that lysine healed cold sores within six days.
Contraindications. Avoid taking large amounts of calcium and lysine at the same time. Lysine can increase how much calcium the body absorbs. Taking calcium along with lysine can increase the amount of calcium in the body.
These three vitamins—C, E, and B12—can work together to provide a comprehensive approach to managing cold sores.
Taking lysine supplements is very safe and does not seem to cause many side effects. Most people can take a daily dose of up to 3 grams (g) of lysine without any side effects. Increasing the dosage of lysine to 10–15 g a day may result in digestive issues, such as: diarrhea.
The cold sore ointment docosanol (Abreva) may shorten the healing time of a cold sore. At the first sign of symptoms, apply it to the affected skin as directed on the package. Use a cotton-tipped swab to put medicine on a cold sore. This helps prevent the spread of the sores to other parts of the body.
If you're taking lysine supplements to prevent an outbreak, take no more than 1 gm per day. A dose of 500 mg a day has been shown to be effective. If you're taking lysine supplements to treat an outbreak, you can take up to 3 g per day. But it's important not to continue this high dose for an extended period of time.
Lysine can increase the absorption of calcium. Use caution when taking large amounts of calcium while supplementing with lysine. While lysine in the diet is considered safe, excessive doses may cause gallstones. There have also been reports of renal dysfunction, including Fanconi syndrome and renal failure.
Vitamin D and Vitamin C are crucial pieces of a healthy immune system. When a person is deficient in either of these, cold sores are much more likely to form.
Lysine may slow or stop the growth of viruses. It may protect against sexual transmission of the herpes virus. It may prevent cold sores (herpes sores) from coming back when taken with vitamin C and bioflavonoids. Lysine may improve how calcium is used.
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