NEXIUM is contraindicated in patients with known hypersensitivity to substituted benzimidazoles or to any component of the formulation. Hypersensitivity reactions may include anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, and urticaria [see Adverse Reactions (6)].
Esomeprazole is not suitable for some people. To make sure it's safe for you, tell your doctor if you: have ever had an allergic reaction to esomeprazole or any other medicine. have liver problems.
Do not use esomeprazole if you are also using medicines containing rilpivirine (Edurant®, Complera®). Using these medicines together may cause unwanted side effects. Esomeprazole may cause a serious type of allergic reaction when used in patients with conditions treated with antibiotics.
You can eat and drink normally while taking esomeprazole. However, it's best to avoid foods that seem to make your indigestion worse – things like rich, spicy and fatty foods. Try to cut down on caffeinated drinks, such as tea, coffee and cola. Reduce or try to avoid alcohol.
Esomeprazole can also affect the way other medicines work. Taking them together can make you more likely to have side effects or stop one of the medicines working as well.
NEXIUM is contraindicated in patients with known hypersensitivity to substituted benzimidazoles or to any component of the formulation. Hypersensitivity reactions may include anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, and urticaria [see Adverse Reactions (6)].
If you take esomeprazole for more than 3 months, the levels of magnesium in your blood may fall. Low magnesium can make you feel tired, confused, dizzy and cause muscle twitches, shakiness and an irregular heartbeat. If you get any of these symptoms, tell your doctor.
This medication may also interact with the following: Antifungals such as itraconazole, ketoconazole, and voriconazole. Certain antivirals for HIV or hepatitis. Certain medications that treat or prevent blood clots such as warfarin.
For short-term relief, your best bet may be an antacid or an H2 blocker. If you have frequent heartburn or a stomach ulcer, your healthcare provider may recommend a PPI instead. They've been around for years and are considered safe and effective treatments.
However scientists and clinicians generally agree that both omeprazole and esomeprazole have the same effects overall, and that one is not superior to another. Whether it is esomeprazole or omeprazole, the best medication is the one that works best for you (with the least amount of side effects).
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